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mea device maestro edge version (Axion BioSystems)

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Axion BioSystems mea device maestro edge version
Mea Device Maestro Edge Version, supplied by Axion BioSystems, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/mea+device%2C+maestro+edge+version/mea+device+maestro+edge+version/pm40262243-80-8-13
Average 90 stars, based on 1 article reviews

mea device maestro edge version - by Bioz Stars, 2026-09

90/100 stars

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Article Title: Development of heart organoid cryopreservation method through Fe 3 O 4 nanoparticles based nanowarming system.
Article Snippet: Funding information Ministry of Food andDrug Safety, Grant/Award Number: 22212MFDS301; National Research Foundation of Korea(NRF), Grant/Award Number: RS-2023-00210807 Abstract Beyond single cell two-dimensional (2D) culture, research on organoids that canmimic human organs is rapidly developing.. However, there are still problems in commercialization and joint research using organoids due to the lack of technology to safely store organoids.. Since organoids are 3D complex structures with a certain size (0.1– 5 mm) beyond the size of cells, the conventional cell-level cryopreservation method using cryoprotectant (CPA) cannot overcome the damage caused by volume change due to osmotic pressure difference and ice nucleation.

Article Title: Modelling myocardial ischemia/reperfusion injury with inflammatory response in human ventricular cardiac organoids
Article Snippet: .. The multi‐electrode array (MEA) plate was transferred to the MEA device, Maestro Edge version (Axion BioSystems Inc.; Atlanta, GA, USA) for measuring the spike amplitude and beat amplitude of field potential under spontaneous beating without electrical stimulation. ..

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Hypoxia/reoxygenation (H/R)‐induced injury in human ventricular cardiac organoids. (A) Modelling process of H/R in ventricular cardiac organoids. (B) Contour plots of flow cytometry analysis for apoptotic cells in control and H/R groups by Annexin V‐FITC/PI‐PE staining. (C) Proportions of early and late apoptosis cells in flow cytometry analysis for control and H/R groups, n = 5 independent replicates. (D) Distribution of TNNT2 (red), TUNEL (green) and DAPI (blue) in control and H/R groups. Scale bars (left), 200 μm. Scale bars (right), 20 μm. (E) MDA concentration in control and H/R groups, n = 7 independent replicates. (F) Relative cytotoxicity of lactate dehydrogenase (LDH) in control and H/R groups, n = 6 independent replicates. (G) Distribution of CMs (TNNT2), ECs (CD31), and fibroblasts (VIM) in control and H/R groups. Scale bars (left), 200 μm. Scale bars (right), 20 μm. (H) Bright‐field microscopy images and schematic representation of MEA‐measured contractility and Beat Amplitude values ( n = 23 electrodes per group) in control and H/R groups. (I) Representative calcium images at active and rest stages in control and H/R groups and the synchronized contraction was shown by calcium flux frequency. Results were expressed as F/F0 (F0 refers to baseline intensity). Scale bar, 200 μm. H/R indicates hypoxia/reoxygenation and VIM indicates Vimentin. Bar and dot plot graphs show mean ± SD. Statistical significance was assessed by unpaired t ‐test (*** p < 0.001).

Journal: Cell Proliferation

Article Title: Modelling myocardial ischemia/reperfusion injury with inflammatory response in human ventricular cardiac organoids

doi: 10.1111/cpr.13762

Figure Lengend Snippet: Hypoxia/reoxygenation (H/R)‐induced injury in human ventricular cardiac organoids. (A) Modelling process of H/R in ventricular cardiac organoids. (B) Contour plots of flow cytometry analysis for apoptotic cells in control and H/R groups by Annexin V‐FITC/PI‐PE staining. (C) Proportions of early and late apoptosis cells in flow cytometry analysis for control and H/R groups, n = 5 independent replicates. (D) Distribution of TNNT2 (red), TUNEL (green) and DAPI (blue) in control and H/R groups. Scale bars (left), 200 μm. Scale bars (right), 20 μm. (E) MDA concentration in control and H/R groups, n = 7 independent replicates. (F) Relative cytotoxicity of lactate dehydrogenase (LDH) in control and H/R groups, n = 6 independent replicates. (G) Distribution of CMs (TNNT2), ECs (CD31), and fibroblasts (VIM) in control and H/R groups. Scale bars (left), 200 μm. Scale bars (right), 20 μm. (H) Bright‐field microscopy images and schematic representation of MEA‐measured contractility and Beat Amplitude values ( n = 23 electrodes per group) in control and H/R groups. (I) Representative calcium images at active and rest stages in control and H/R groups and the synchronized contraction was shown by calcium flux frequency. Results were expressed as F/F0 (F0 refers to baseline intensity). Scale bar, 200 μm. H/R indicates hypoxia/reoxygenation and VIM indicates Vimentin. Bar and dot plot graphs show mean ± SD. Statistical significance was assessed by unpaired t ‐test (*** p < 0.001).

Article Snippet: The multi‐electrode array (MEA) plate was transferred to the MEA device, Maestro Edge version (Axion BioSystems Inc.; Atlanta, GA, USA) for measuring the spike amplitude and beat amplitude of field potential under spontaneous beating without electrical stimulation.

Techniques: Flow Cytometry, Control, Staining, TUNEL Assay, Concentration Assay, Microscopy